From August 29-September 2, 2015, at the invitation of His All-Holiness Ecumenical Patriarch Bartholomew, a Synaxis of Hierarchs of the Ecumenical Throne gathered from all over the world at the Church of the Holy Trinity in Taksim Square. His All-Holiness delivered the Keynote Address to over 140 Hierarchs of the Throne, speaking to developments and challenges of the Ecumenical Patriarchate and the Orthodox Church in general during recent years.

Introductions were presented by senior Metropolitans on ecclesiastical, pastoral and theological initiatives and ministries, including the forthcoming Holy and Great Council, the regional Assemblies of Bishops, the World Council and European Council of Churches, the Theological Dialogues with the Roman Catholic Church, the Pre-Chalcedonian Churches, the World Lutheran Federation, the Anglican Communion, the World Communion on Reformed Churches and the Old Catholic Church.

Further presentations were delivered on contemporary vital issues, such as the Orthodox response to bioethical issues, the root and impact of climate change, as well as the phenomenon of immigration and the pastoral ministry of the Church toward the humanitarian refugee crisis.

On September 1, 2015, the beginning of the ecclesiastical year, His All-Holiness presided over the Divine Liturgy, together with the Hierarchs in attendance. There followed the traditional Act of the Signing of the New Indiction.